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What is Boniva?

Boniva (ibandronate) is a medication primarily used to treat osteoporosis in postmenopausal women. It belongs to the bisphosphonate class of drugs, which work by slowing bone loss and increasing bone density. It's typically taken orally once a month, and common side effects may include gastrointestinal issues. Boniva helps reduce the risk of fractures, particularly in the spine and hips, in postmenopausal women with osteoporosis.

Boniva (ibandronate) is typically taken orally, usually once a month. Here are some general instructions on how to take Boniva:

  1. Timing: Take Boniva in the morning, at least 60 minutes before your first meal, drink, or other medication of the day. It's important to take it on an empty stomach to maximize absorption.

  2. With Water: Swallow the tablet whole with a full glass (6 to 8 ounces) of plain water. Do not chew or suck on the tablet, as this can interfere with its effectiveness.

  3. Stay Upright: After taking the tablet, remain upright (sitting, standing, or walking) for at least 60 minutes. This helps prevent irritation to the esophagus and ensures proper absorption of the medication.

  4. Avoid Food and Other Medications: Do not eat, drink (other than plain water), or take any other medications, including vitamins or supplements, for at least 60 minutes after taking Boniva.

  5. Monthly Schedule: Take Boniva once a month on the same day each month. It's helpful to choose a specific day to take the medication and mark it on your calendar to ensure consistency.

  6. Follow Doctor's Instructions: Always follow your healthcare provider's instructions regarding dosage and frequency when taking Boniva. Do not exceed the prescribed dose or take it more frequently than recommended.

  7. Continue Treatment: Osteoporosis treatment with Boniva is typically long-term. Continue taking it as directed by your doctor, even if you start feeling better.

  8. Regular Check-ups: Your doctor may recommend periodic bone density tests and follow-up appointments to monitor your progress and adjust your treatment plan as needed.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about how to take Boniva or if you experience any unusual symptoms while taking the medication.


When taking Boniva (ibandronate), it's essential to be aware of certain precautions to ensure safe and effective use of the medication. Here are some precautions to consider:

  1. Medical History: Inform your healthcare provider about your complete medical history, especially if you have any kidney problems, low blood calcium levels, dental problems, esophageal issues, or if you are unable to sit or stand upright for at least 60 minutes.

  2. Allergies: If you have a known allergy to ibandronate or any other bisphosphonates, inform your doctor before starting Boniva.

  3. Pregnancy and Breastfeeding: Boniva is generally not recommended during pregnancy or breastfeeding, as its safety in these situations has not been established. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

  4. Other Medications: Inform your healthcare provider about all medications, vitamins, and supplements you are currently taking, as they may interact with Boniva. In particular, certain medications, such as antacids, calcium supplements, or NSAIDs (non-steroidal anti-inflammatory drugs), may interfere with the absorption of Boniva.

  5. Dental Health: Bisphosphonates like Boniva have been associated with a rare but severe side effect called osteonecrosis of the jaw (ONJ), which involves the death of bone tissue in the jaw. Before starting Boniva, undergo a dental examination and necessary dental treatments. While taking Boniva, practice good oral hygiene and promptly report any dental problems to your dentist.

  6. Bone Fractures: There have been reports of unusual fractures of the thigh bone in individuals taking bisphosphonates like Boniva for long periods. Inform your doctor if you experience new or unusual pain in your hips, thighs, or groin while taking Boniva.

  7. Esophageal Issues: Boniva tablets can cause irritation or ulceration of the esophagus. To minimize this risk, take Boniva with a full glass of water while in an upright position and avoid lying down for at least 60 minutes afterward.

  8. Regular Monitoring: Your doctor may recommend periodic bone density tests and follow-up appointments to monitor your response to Boniva and adjust your treatment plan as needed.

Side Effects of Boniva

Common side effects of Boniva (ibandronate) include gastrointestinal discomfort such as upset stomach, nausea, vomiting, diarrhea, or constipation. Additionally, some individuals may experience musculoskeletal pain, including joint or muscle pain. Rare but severe side effects may include osteonecrosis of the jaw (ONJ), characterized by jaw pain, swelling, or numbness, and atypical fractures of the thigh bone.

Other potential adverse reactions include allergic reactions such as rash, itching, or difficulty breathing. It's essential to promptly report any unusual symptoms or side effects to your healthcare provider while taking Boniva, as some adverse reactions may require medical attention.


How often do I need to take Boniva?

Boniva is typically taken once a month, either orally or intravenously, as prescribed by your healthcare provider. It's crucial to follow the recommended dosage and schedule provided by your doctor for optimal effectiveness.

Can I take other medications or supplements with Boniva?

It's essential to consult your healthcare provider before taking any other medications, vitamins, or supplements alongside Boniva. Some drugs and supplements may interact with Boniva, affecting its absorption or increasing the risk of side effects.

What should I do if I miss a dose of Boniva?

If you miss a dose of Boniva, take it as soon as you remember, unless it's close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take two doses of Boniva on the same day to make up for a missed dose.

How long do I need to take Boniva?

Treatment with Boniva is typically long-term for managing osteoporosis. Your healthcare provider will determine the duration of treatment based on your individual condition and response to the medication. It's essential to continue taking Boniva as prescribed, even if you start feeling better, to maintain bone health and reduce the risk of fractures. Regular monitoring and follow-up appointments with your doctor are recommended to assess the ongoing need for Boniva therapy.

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Esther Mae W

November 4, 2022

Excellent service on setting up our account

Robert G

October 27, 2022

Great service! The pills arrived even faster than I expected.

Stephen D

October 14, 2022

Your operators are always courteous and knowledgeable. Very good service.


October 13, 2022

I've been a Canadian Med Center customer for about 6 years now. In all that time there was never once that I considered taking my business elsewhere. They do a great job and the people they contract with are also super.


October 5, 2022

Cheaper and efficient.

Dorothy Serrie S

October 4, 2022

Always appreciate their prompt service but especially appreciate their hanging in there when there was difficulty getting my doctor to renew my prescription!

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Canadian Med Center sells genuine Boniva® manufactured by F. Hoffmann-La Roche Ltd. It also sells generic Ibandronate. These generic products neither originate from nor are they authorized by F. Hoffmann-La Roche Ltd. or Genentech, Inc. All brands listed here are the trademarks of their respective owners and Canadian Med Center is not affiliated with them in any way.

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