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What is Combigan?

Combigan is a medication used to treat high pressure inside the eye from certain conditions such as glaucoma, ocular hypertension, or other diseases. Blindness can be prevented by this medication as it lowers the high pressure inside the eye.

How Does Combigan Work?

Combigan contains both brimonidine and timolol. Brimonidine helps to reduce pressure inside the eye by decreasing the amount of fluid formed in the eye and by allowing better fluid drainage. Timolol reduces pressure inside the eye by decreasing the amount of fluid formed there, and is also a beta-blocker.



  • Use Combigan exactly as prescribed by a doctor
  • Follow the directions outlined on your prescription label
  • Tilt your head up slightly. Pull the lower eyelid down to create a small space. Hold the dropper with the tip down above the eye as you squeeze a drop out
  • Only use as many drops as your doctor has prescribed
  • Wait at least 5 minutes between drops
  • Wait at least 10 minutes before using any other eye drops that have been prescribed from your doctor



Cautions and Precautions

Do not use this medication when wearing contact lenses, as Combigan can contain an ingredient that may discolor contacts

  • After taking this medicine, wait 15 minutes or more after use before putting contact lenses in eye
  • Always wash your hands prior to taking
  • Do not touch the tip of the dropper in order to avoid infection
  • Do not place the dropper directly on the eye
  • If the liquid has changed color or texture, do not use. You may need to call your pharmacist for a new medicine.
  • If you have an eye infection or need eye surgery, tell your doctor immediately
  • Store this medicine at room temperature in a dry place with the bottle kept tightly closed when not in use
  • If you are allergic to brimonidine, timolol, or apraclonidine, tell your doctor
  • Before using this medicine, consult your doctor. You should not use this medication if you have certain medical conditions such as: lung disease, irregular heartbeats or arrhythmias, and certain types of heart disease
  • Inform your doctor if you have a medical history of kidney, liver, heart, or blood vessel disease.
  • Also inform your doctor if you have a history of blood circulation disorders, dizziness after standing, diabetes, depression, hyperthyroidism, muscle weakness disorders, or severe allergies

Side Effects of Combigan

There is the possibility of certain side effects when taking a Combigan prescription. If you have hives, difficulty breathing, or swelling around the face, mouth, or throat, seek emergency medical help immediately as these are signs of an allergic reaction.

Common side effects may include:

  • Blurred vision
  • Short-term burning, stinging, redness, or itching of the eye
  • Watery eyes
  • Dry eyes
  • Dry mouth
  • Headache
  • Dizziness
  • Drowsiness

Call a doctor if you experience more serious side effects such as:

  • Vision changes
  • Eye pain, swelling, or discharge
  • A slow and irregular heartbeat
  • Muscle weakness
  • Eye sensitivity to light
  • Fatigue
  • Mood changes
  • A feeling of cold, numb, or painful hands
  • Swollen feet or ankles
  • Unexplained weight gain
  • Shortness of breath
  • Trouble breathing
  • Chest pain
  • Weakness on one side of the body
  • Mental confusion
  • Slurred speech
  • Fainting



What is glaucoma?

Glaucoma can be caused by excess fluid that increases pressure within the eye. The increased pressure can damage the eye’s optic nerve. The most common form of glaucoma is open-angle glaucoma.

Is there a cure for glaucoma?

Although there is no cure for glaucoma, reducing eye pressure can help mitigate the risk of vision loss associated with this condition. High eye pressure can slowly damage your optic nerve, that’s why treatment for high pressure is important.

What did your doctor prescribe Combigan?

It is common for prescription eye drops to be used to reduce high pressure in the eye. Combigan has been proen to lower eye pressure in glaucoma patients.

Real People, Trustworthy Reviews

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Esther Mae W

November 4, 2022

Excellent service on setting up our account

Robert G

October 27, 2022

Great service! The pills arrived even faster than I expected.

Stephen D

October 14, 2022

Your operators are always courteous and knowledgeable. Very good service.


October 13, 2022

I've been a Canadian Med Center customer for about 6 years now. In all that time there was never once that I considered taking my business elsewhere. They do a great job and the people they contract with are also super.


October 5, 2022

Cheaper and efficient.

Dorothy Serrie S

October 4, 2022

Always appreciate their prompt service but especially appreciate their hanging in there when there was difficulty getting my doctor to renew my prescription!

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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