DON’T MISS THE Price Drop! For Cymbalta (Duloxetine) or Cymbalta (Duloxetine) - Also known as Yentreve Internationally or Duloxetine (Generic)
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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?


Buying Cymbalta from a Canadian Pharmacy

If you were looking to save money on purchasing Cymbalta (Duloxetine) then a Canadian Pharmacy service like ours is a great option. Cymbalta is available in both brand and generic from our Canadian pharmacy at substantially discounted prices. Save over 80% on generic Cymbalta (and brand-name), shipped directly to your door. For your convenience, we offer this product from various countries if available. Simply call us if you have any questions about ordering.

How does Cymbalta work ?

Cymbalta or Duloxetine is a serotonin-norepinephrine reuptake inhibitor antidepressant class of drug which is prescribed for the treatment of major depressive disorder, diabetic neuropathy, generalized anxiety disorder, and osteoarthritis pain. Cymbalta is also prescribed to patients suffering from fibromyalgia. The drug is manufactured and marketed by Eli Lily and has been approved by the majority of drug regulatory authorities around the world for the treatment of aforementioned problems. The drug is found effective in improving the balance of the chemicals in the brain that are responsible for depression and diabetic peripheral neuropathic pain.

Cymbalta must be taken exactly as directed by the healthcare provider to have the best effect of the medication. Following instructions must be kept in mind while consuming Cymbalta.

  • The prescribed dosage of the drug should never be increased or decreased without prior consulting with the doctor.
  • Sudden stopping of the medication can result in unpleasant side effects.
  • Patients should not open, break or crush the tablet. They are advised to swallow whole tablet with a glass full of water.
  • This drug should be initiated with a low dose that should be gradually increased over the period of time.

Cymbalta Dosage

Cymbalta dosages are determined depending upon the factors like medical condition for which the patients are being treated, other medical conditions of the patients and the intake of any other medications taken by the patients.

Depression - The recommended Cymbalta dose for depression is either 20 mg twice in a day or 30 mg twice in day. Patients are advised to avoid dosage above 60 mg per day.

Neuropathic Pain – Patients suffering from peripheral diabetic neuropathy pain are recommended with the dosage of 60 mg once in a day. Individuals having kidney problems are advised to start with a lower dose.

Generalized Anxiety Disorder & Fibromyalgia – GAD and Fibromyalgia patients are advised to start with the dose of 30 mg once in a day, which after one week time is increased to 60 mg in a day.

Musculoskeletal Pain – The starting dose for the treatment of musculoskeletal pain like arthritis or back pain is 60 mg once in a day. However, the patients are advised to start with 30 mg in a day in order to get accustomed to the drug.

Missed and Overdose of Duloxetine

In case if anyone has missed a dose of Duloxetine, then the person should immediately take the drug upon remembering it. If it is almost the time for next dose, then patients should skip the missed dose and resume with the regular dosing schedule. Double dose of the drug should be strictly avoided.

The effect of the overdose varies depending upon the amount of Cymbalta consumed and whether it was taken with any other medications or not. Overdose symptoms that can be experienced by the victims are vomiting, drowsiness and seizures. The overdosed individual should be immediately provided with emergency medical help. Immediate treatment options for overdosed victims include pumping the stomach or administering fluids through an intravenous line.

Cymbalta Storage

Cymbalta must be ideally stored between the temperatures 25°C to 30°C. The drug should be kept away from direct sunlight and must be protected from moisture. Duloxetine must also be kept away from children and pets. All expired and unused drugs should be safely disposed.


Certain warnings are associated with the use of Duloxetine and patients are should be made aware of these precautions and warnings. Some of the warnings that must be kept in mind by the patients include:

  • This drug may cause drowsiness so patients using this drug are advised to avoid driving or operating heavy machinery while taking this drug.
  • Women who are pregnant or planning pregnancy should avoid using this drug.
  • Drinking alcohol while taking Cymbalta may cause severe liver damage.
  • Duloxetine may cause drop in blood pressure so the patients using this drug must be careful while moving from a lying or sitting position. This drug
  • may cause dizziness or light headedness feeling at the start of the treatment.
  • This drug starts showing is effect after two to four weeks of continuously use. Therefore, patients must continue using this drug for the prescribed
  • period in order to have the best effect of the medication.
  • This drug is not recommended for use in children and adolescents under 18 years of age.

Side Effects

Some of the patients prescribed with Duloxetine may experience common side effects associated with the drug. Although it is not necessary for all individuals taking this drug to experience side effects because each person reacts differently to this drug. Some of the common side effects that can occur are:

  • Nausea
  • Dry mouth
  • Constipation
  • Loss of appetite
  • Tiredness, drowsiness, or increased sweating

Severe Side Effects of Duloxetine

Severe side effects associated with Cymbalta are uncommon. One in thousands of patients might experience sign of severe side effects. Still patients must be aware of severe side effects associated with the drug so that they take the necessary step upon experiencing any of these side effects. Severe side effects of Cymbalta include:

  • Fast heartbeat
  • Hallucinations
  • Loss of coordination
  • Severe dizziness
  • Severe nausea/vomiting/diarrhea
  • Twitching muscles
  • Unexplained fever
  • Unusual agitation
  • Restlessness
  • Teeth Grinding

Duloxetine Drug Interaction

Patients are advised to inform their doctor about all prescription, over-the-counter medicines and supplements they are taking or planning to take. It is advised because Duloxetine is known to interact with certain drugs. Antibiotics and psychotic disorder medicines are recommended to be avoided while taking Cymbalta because these combinations of drugs can potentially lead to life threatening condition. Some other drugs that should be avoided while taking Duloxetine include:

  • NSAID pain relievers
  • Blood thinners like Warfarin
  • Aspirin
  • Tramadol
  • Tryptophan
  • Carbolith
  • Zyvox
  • Migraine medicines

MAOI antidepressant like isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, and tranylcypromine should be avoided while taking Cymbalta. Patients who have taken any of the MAOI antidepressant should not start Duloxetine within the two weeks. Patients using Cymbalta should not start any of these MAOI antidepressants, as these drugs can only be started after 5 days of stopping Duloxetine.

Patients suffering from following diseases are advised to consult doctor prior starting treatment with Cymbalta:

  • Liver or Kidney disease
  • Seizures
  • Blood clotting disorder
  • Glaucoma
  • High blood pressure
  • Bipolar disorder


Q: Why is Cymbalta prescribed?

A: Cymbalta is commonly used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old.

Q: Are there any other reasons I could be prescribed Cymbalta?

A: Yes, Cymbalta is also used in adults to treat fibromyalgia or chronic muscle/joint pain and to treat pain caused by nerve damage in adults with diabetes 

Q: Does Cymbalta have a generic alternative?

A: Duloxetine (Generic) is available for purchase at a lower cost than the brand name! 

Q: What if I miss a dose of Cymbalta?

A: Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Q: How should I store this medication?

A: Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

IMPORTANT NOTE: The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
IMPORTANT NOTE: Please note that not all medications, including any referenced on this page, are dispensed from our affiliated Canadian pharmacy. The medications in your order may be filled and shipped from an approved International fulfillment center located in a country other than Canada. In addition to dispensing medications from our Canadian pharmacy, medication orders are also filled and shipped from international fulfillment centers that are approved by the regulatory bodies from their respective countries. Medication orders are filled and shipped from approved fulfillment centers around the world including, but not limited to, Canada, Singapore, United Kingdom, New Zealand, Turkey, Mauritius, India, Australia, and the United States. The items in your order may be filled and shipped from any one of the above jurisdictions. The products are sourced from various countries including, but not limited to, Canada, United Kingdom, New Zealand, Turkey, India, Australia, and the United States. All of our affiliated fulfillment centers have been approved by the regulatory bodies from their respective countries.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-205-1510 and a member of our CareTeam will be happy to assist you.

Call 1-877-205-1510
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

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Very efficient service. Quality products and friendly personnel.
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very efficient and courteous and customer orientated!!
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I ALWAYS have a great experience with y'all. I work with Nicole and she is delightful and most helpful. She answers all of my questions, including the state of the weather in Vancouver compared to ours in southeast Georgia USA.
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It was a refill order and the agent was very nice. Very helpful- no complaints
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We have had good experiences with this firm..
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The service is Excellent; extremely good follow through and very professional, friendly staff
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Canada med ctr makes getting my meds effortless!
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No problems
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I am pleased with the service.
David January 18, 2020

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Easy and very cost effective -- a great alternative to the extortionary US drug prices for the exact same prescription, and with very nice customer service!
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