Canada Drug Center > Cymbalta (Duloxetine)
DON’T MISS THE Price Drop! For Cymbalta (Duloxetine) or Cymbalta (Duloxetine) - Also known as Yentreve Internationally or Duloxetine (Generic)
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1. Strength

30mg60mg20mg40mg

2. Quantity

Duloxetine (Generic)
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100 $96.00 $0.96 BUY
Cymbalta (Duloxetine)
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28 $68.00 $2.43 BUY
56 $116.00 $2.07 BUY
84 $171.00 $2.04 BUY
112 $220.00 $1.96 BUY
Cymbalta (Duloxetine) - Also known as Yentreve Internationally
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Description

Cymbalta or Duloxetine is a serotonin-norepinephrine reuptake inhibitor antidepressant class of drug which is prescribed for the treatment of major depressive disorder, diabetic neuropathy, generalized anxiety disorder, and osteoarthritis pain. Cymbalta is also prescribed to patients suffering from fibromyalgia. The drug is manufactured and marketed by Eli Lily and has been approved by the majority of drug regulatory authorities around the world for the treatment of aforementioned problems. The drug is found effective in improving the balance of the chemicals in the brain that are responsible for depression and diabetic peripheral neuropathic pain.

Directions

Cymbalta must be taken exactly as directed by the healthcare provider to have the best effect of the medication. Following instructions must be kept in mind while consuming Cymbalta.

  • The prescribed dosage of the drug should never be increased or decreased without prior consulting with the doctor.
  • Sudden stopping of the medication can result in unpleasant side effects.
  • Patients should not open, break or crush the tablet. They are advised to swallow whole tablet with a glass full of water.
  • This drug should be initiated with a low dose that should be gradually increased over the period of time.

Cymbalta Dosage

Cymbalta dosages are determined depending upon the factors like medical condition for which the patients are being treated, other medical conditions of the patients and the intake of any other medications taken by the patients.

Depression - The recommended Cymbalta dose for depression is either 20 mg twice in a day or 30 mg twice in day. Patients are advised to avoid dosage above 60 mg per day.

Neuropathic Pain – Patients suffering from peripheral diabetic neuropathy pain are recommended with the dosage of 60 mg once in a day. Individuals having kidney problems are advised to start with a lower dose.

Generalized Anxiety Disorder & Fibromyalgia – GAD and Fibromyalgia patients are advised to start with the dose of 30 mg once in a day, which after one week time is increased to 60 mg in a day.

Musculoskeletal Pain – The starting dose for the treatment of musculoskeletal pain like arthritis or back pain is 60 mg once in a day. However, the patients are advised to start with 30 mg in a day in order to get accustomed to the drug.

Missed and Overdose of Duloxetine

In case if anyone has missed a dose of Duloxetine, then the person should immediately take the drug upon remembering it. If it is almost the time for next dose, then patients should skip the missed dose and resume with the regular dosing schedule. Double dose of the drug should be strictly avoided.

The effect of the overdose varies depending upon the amount of Cymbalta consumed and whether it was taken with any other medications or not. Overdose symptoms that can be experienced by the victims are vomiting, drowsiness and seizures. The overdosed individual should be immediately provided with emergency medical help. Immediate treatment options for overdosed victims include pumping the stomach or administering fluids through an intravenous line.

Cymbalta Storage

Cymbalta must be ideally stored between the temperatures 25°C to 30°C. The drug should be kept away from direct sunlight and must be protected from moisture. Duloxetine must also be kept away from children and pets. All expired and unused drugs should be safely disposed.

Cautions

Certain warnings are associated with the use of Duloxetine and patients are should be made aware of these precautions and warnings. Some of the warnings that must be kept in mind by the patients include:

  • This drug may cause drowsiness so patients using this drug are advised to avoid driving or operating heavy machinery while taking this drug.
  • Women who are pregnant or planning pregnancy should avoid using this drug.
  • Drinking alcohol while taking Cymbalta may cause severe liver damage.
  • Duloxetine may cause drop in blood pressure so the patients using this drug must be careful while moving from a lying or sitting position. This drug
  • may cause dizziness or light headedness feeling at the start of the treatment.
  • This drug starts showing is effect after two to four weeks of continuously use. Therefore, patients must continue using this drug for the prescribed
  • period in order to have the best effect of the medication.
  • This drug is not recommended for use in children and adolescents under 18 years of age.
Side Effects

Some of the patients prescribed with Duloxetine may experience common side effects associated with the drug. Although it is not necessary for all individuals taking this drug to experience side effects because each person reacts differently to this drug. Some of the common side effects that can occur are:

  • Nausea
  • Dry mouth
  • Constipation
  • Loss of appetite
  • Tiredness, drowsiness, or increased sweating

Severe Side Effects of Duloxetine

Severe side effects associated with Cymbalta are uncommon. One in thousands of patients might experience sign of severe side effects. Still patients must be aware of severe side effects associated with the drug so that they take the necessary step upon experiencing any of these side effects. Severe side effects of Cymbalta include:

  • Fast heartbeat
  • Hallucinations
  • Loss of coordination
  • Severe dizziness
  • Severe nausea/vomiting/diarrhea
  • Twitching muscles
  • Unexplained fever
  • Unusual agitation
  • Restlessness
  • Teeth Grinding

Duloxetine Drug Interaction

Patients are advised to inform their doctor about all prescription, over-the-counter medicines and supplements they are taking or planning to take. It is advised because Duloxetine is known to interact with certain drugs. Antibiotics and psychotic disorder medicines are recommended to be avoided while taking Cymbalta because these combinations of drugs can potentially lead to life threatening condition. Some other drugs that should be avoided while taking Duloxetine include:

  • NSAID pain relievers
  • Blood thinners like Warfarin
  • Aspirin
  • Tramadol
  • Tryptophan
  • Carbolith
  • Zyvox
  • Migraine medicines

MAOI antidepressant like isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, and tranylcypromine should be avoided while taking Cymbalta. Patients who have taken any of the MAOI antidepressant should not start Duloxetine within the two weeks. Patients using Cymbalta should not start any of these MAOI antidepressants, as these drugs can only be started after 5 days of stopping Duloxetine.

Patients suffering from following diseases are advised to consult doctor prior starting treatment with Cymbalta:

  • Liver or Kidney disease
  • Seizures
  • Blood clotting disorder
  • Glaucoma
  • High blood pressure
  • Bipolar disorder
IMPORTANT NOTE: The information provided on the https://www.canadianmedcenter.com website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
IMPORTANT NOTE: Please note that not all medications, including any referenced on this page, are dispensed from our affiliated Canadian pharmacy. The medications in your order may be filled and shipped from an approved International fulfillment center located in a country other than Canada. In addition to dispensing medications from our Canadian pharmacy, medication orders are also filled and shipped from international fulfillment centers that are approved by the regulatory bodies from their respective countries. Medication orders are filled and shipped from approved fulfillment centers around the world including, but not limited to, Canada, Singapore, United Kingdom, New Zealand, Turkey, Mauritius, India, Australia, and the United States. The items in your order may be filled and shipped from any one of the above jurisdictions. The products are sourced from various countries including, but not limited to, Canada, United Kingdom, New Zealand, Turkey, India, Australia, and the United States. All of our affiliated fulfillment centers have been approved by the regulatory bodies from their respective countries.

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What's the difference between generic drugs and brand name drugs?


What's the difference between the branded products you sell and the ones I get locally?
The branded drugs we sell are chemically and therapeutically no different from the ones you get in your local pharmacy. They both generally come from the same exact manufacturer. Generally, the main difference* is in the packaging and the price. Our packaging may be different from what you get locally, but we're also much cheaper.

* Other differences may include differences in trade name, form, and general appearance.

Why are there packaging differences?
Due to differences in government regulation, different countries have different packaging requirements. For example, a product in Canada (or any other country) will have different packaging than the same product in the US even though both drugs are chemically and therapeutically equivalent and are generally manufactured by the same exact company.

Why are your drugs so much cheaper?
Due to government price controls, medications from Canada and many other countries are often significantly cheaper than in the United States. Also, other countries may have more affordable generic versions of drugs, which may not yet be available in the US.

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