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What is Estrogel Used For?

Estrogel is a medication used primarily in hormone replacement therapy (HRT) for women who are experiencing symptoms of menopause. It contains estradiol, which is a form of the hormone estrogen. Estrogen levels decline during menopause, leading to symptoms such as hot flashes, vaginal dryness, mood swings, and night sweats. Estrogel helps alleviate these symptoms by supplementing the body with estrogen.

Estrogel is typically applied topically to the skin. It comes in the form of a gel, which is absorbed through the skin and into the bloodstream. The usual dose is applied once daily, usually in the morning. It's important to follow the instructions provided by your healthcare provider or as indicated on the medication packaging. Estrogel should be applied to clean, dry skin on areas such as the arms, thighs, or abdomen. It's important to rotate application sites to avoid irritation.

Side Effects of Estrogel

Like any medication, Estrogel can cause side effects. Common side effects may include:

  1. Breast tenderness or enlargement
  2. Headache
  3. Nausea
  4. Vaginal discharge or irritation
  5. Mood changes
  6. Fluid retention

Less common but more serious side effects may include:

  1. Blood clots
  2. Stroke
  3. Heart attack
  4. Breast cancer
  5. Endometrial cancer

If you experience any unusual or severe side effects while using Estrogel, it's important to contact your healthcare provider immediately.


Before using Estrogel, it's important to discuss your medical history and any other medications you may be taking with your healthcare provider. Estrogel may not be suitable for everyone, especially those with a history of certain medical conditions such as blood clots, stroke, heart disease, or breast cancer.

Additionally, Estrogel should not be used during pregnancy or breastfeeding. It's important to use effective contraception if you are of childbearing age and sexually active while using Estrogel.


How long does it take for Estrogel to work?

Estrogel may start to alleviate symptoms of menopause within a few weeks of starting treatment, but it may take several months to experience the full benefits.

Can Estrogel be used for birth control?

No, Estrogel is not a form of birth control and should not be used for this purpose.

Can men use Estrogel?

Estrogel is specifically intended for use in women undergoing hormone replacement therapy and is not recommended for use in men.

How should Estrogel be stored?

Estrogel should be stored at room temperature, away from moisture and heat. Do not freeze the gel.

Can Estrogel be used indefinitely?

Your healthcare provider should determine the duration of your Estrogel treatment based on your individual needs and medical history. Some women may use Estrogel for a short period, while others may require long-term treatment. It's important to review your treatment plan with your healthcare provider regularly.

Real People, Trustworthy Reviews

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Esther Mae W

November 4, 2022

Excellent service on setting up our account

Robert G

October 27, 2022

Great service! The pills arrived even faster than I expected.

Stephen D

October 14, 2022

Your operators are always courteous and knowledgeable. Very good service.


October 13, 2022

I've been a Canadian Med Center customer for about 6 years now. In all that time there was never once that I considered taking my business elsewhere. They do a great job and the people they contract with are also super.


October 5, 2022

Cheaper and efficient.

Dorothy Serrie S

October 4, 2022

Always appreciate their prompt service but especially appreciate their hanging in there when there was difficulty getting my doctor to renew my prescription!

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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