Thousands of 5-Star Reviews From Real Customers - Find Out Why Our Customers Love Us Here!
Canadian Med Center Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Available 7 Days a Week


Express shipping

May be available upon request

Lowest Price, Guaranteed

match price or beat it by 10% *

Life-Time Free shipping

Find out if you're eligible!

  • Delivery time is between 8-14 business days.
  • Express shipping may be available upon request

What is Vivelle Dot?

Vivelle Dot is a brand name for a medication containing estradiol, which is a form of estrogen, a hormone primarily responsible for female sexual development and reproductive function. It's used in hormone replacement therapy (HRT) to treat symptoms of menopause, such as hot flashes, vaginal dryness, and mood swings. Estradiol can also help prevent osteoporosis in postmenopausal women.

Vivelle Dot comes in the form of a transdermal patch, which means it's applied to the skin. The patch releases estradiol through the skin and into the bloodstream over time. Typically, it's applied once or twice a week to clean, dry skin on the lower abdomen or buttocks. It's important to rotate the application site to prevent skin irritation.

Side Effects of Estradiol

Common side effects of Vivelle Dot may include:

  • Skin irritation at the application site
  • Headaches
  • Breast tenderness
  • Nausea
  • Bloating
  • Mood changes

Less common but potentially serious side effects include:

  • Blood clots
  • Stroke
  • Heart attack
  • Breast cancer
  • Uterine cancer
  • Dementia in women aged 65 and older


Medical History: Inform your doctor about your medical history, especially if you have a history of blood clots, stroke, heart disease, liver problems, or breast cancer.

Regular Check-ups: Regularly monitor your health and attend follow-up appointments with your healthcare provider to assess the need for continued hormone replacement therapy.

Smoking: Avoid smoking while using Vivelle Dot, as it can increase your risk of blood clots, stroke, and heart attack.

Other Medications: Inform your doctor about all medications, vitamins, and supplements you are taking, as they may interact with estradiol.


How long does it take for Vivelle Dot to start working?

Some women may experience relief from symptoms like hot flashes within a few weeks of starting treatment, while others may take longer. It's essential to give it time and discuss any concerns with your doctor.

Can Vivelle Dot be used to prevent pregnancy?

No, Vivelle Dot is not a form of birth control and should not be used to prevent pregnancy. If contraception is needed, alternative methods should be discussed with a healthcare provider.

Can Vivelle Dot be used during breastfeeding?

It's generally not recommended to use Vivelle Dot during breastfeeding, as estradiol can pass into breast milk and may harm the nursing infant. If hormone replacement therapy is necessary, alternative options should be discussed with a healthcare provider.

What should I do if I forget to apply a patch?

If you miss a dose, apply the patch as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How should Vivelle Dot patches be disposed of?

Used patches should be folded in half with the sticky sides together and safely discarded, out of reach of children and pets. Unused or expired patches should be disposed of according to local regulations or returned to a pharmacy for proper disposal.

Real People, Trustworthy Reviews

See what others are saying about their experience!

Esther Mae W

November 4, 2022

Excellent service on setting up our account

Robert G

October 27, 2022

Great service! The pills arrived even faster than I expected.

Stephen D

October 14, 2022

Your operators are always courteous and knowledgeable. Very good service.


October 13, 2022

I've been a Canadian Med Center customer for about 6 years now. In all that time there was never once that I considered taking my business elsewhere. They do a great job and the people they contract with are also super.


October 5, 2022

Cheaper and efficient.

Dorothy Serrie S

October 4, 2022

Always appreciate their prompt service but especially appreciate their hanging in there when there was difficulty getting my doctor to renew my prescription!

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-205-1510 and a member of our CareTeam will be happy to assist you.

Call 1-877-205-1510
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.