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What is Zoloft?

Zoloft, known by its generic name sertraline, is a prescription medication primarily used to treat depression, anxiety disorders, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs), which work by increasing the levels of serotonin, a neurotransmitter in the brain associated with mood regulation.

Zoloft is typically taken orally, usually once daily either in the morning or evening, with or without food. The dosage will depend on the condition being treated and individual response to the medication. It's essential to follow the dosage instructions provided by your healthcare provider to achieve the best results.

Side Effects of Zoloft

Common side effects of Zoloft may include:

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Trouble sleeping (insomnia)
  • Dry mouth
  • Fatigue
  • Loss of appetite
  • Sexual dysfunction (such as decreased libido, erectile dysfunction, or difficulty achieving orgasm)

Serious side effects are rare but may include:

  • Suicidal thoughts or behavior, especially in young adults or adolescents
  • Serotonin syndrome, characterized by symptoms like confusion, hallucinations, fever, sweating, shivering, rapid heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea
  • Allergic reactions, such as rash, itching, swelling, severe dizziness, or trouble breathing
  • Seizures
  • Abnormal bleeding or bruising
  • Manic episodes in individuals with bipolar disorder

It's crucial to contact your healthcare provider if you experience any severe or concerning side effects while taking Zoloft.


Before taking Zoloft, inform your healthcare provider about any medical conditions you have, especially:

  • History of bipolar disorder or mania
  • History of seizures
  • Liver or kidney disease
  • Bleeding disorders
  • Diabetes
  • History of suicidal thoughts or attempts
  • Any allergies to medications

Additionally, Zoloft may interact with other medications, including blood thinners, other antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs), or herbal supplements. It's essential to inform your healthcare provider about all medications and supplements you are taking to avoid potentially harmful interactions.

Zoloft should not be stopped abruptly, as it may cause withdrawal symptoms. If you wish to discontinue Zoloft, consult your healthcare provider, who can gradually taper the dosage to minimize withdrawal effects.


How long does it take for Zoloft to start working?

It may take several weeks for Zoloft to reach its full therapeutic effect. Some individuals may notice improvements in symptoms within the first few weeks, while others may require more time.

Can Zoloft be taken during pregnancy?

Zoloft should only be used during pregnancy if the potential benefits outweigh the risks. It's essential to discuss the risks and benefits with your healthcare provider, as untreated maternal depression or anxiety can also pose risks to the fetus.

Can Zoloft be taken with alcohol?

It's generally recommended to avoid alcohol while taking Zoloft, as it may increase the risk of side effects and worsen symptoms of depression or anxiety.

Is Zoloft addictive?

Zoloft is not considered addictive in the same way as substances like opioids or stimulants. However, suddenly stopping Zoloft can lead to withdrawal symptoms, so it should be tapered off gradually under medical supervision when discontinuing treatment.

Can Zoloft cause weight gain?

Weight gain is a potential side effect of Zoloft, although not everyone experiences it. If you notice significant changes in weight while taking Zoloft, discuss this with your healthcare provider. They may recommend dietary changes or adjustments to your medication regimen if necessary.

Real People, Trustworthy Reviews

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Esther Mae W

November 4, 2022

Excellent service on setting up our account

Robert G

October 27, 2022

Great service! The pills arrived even faster than I expected.

Stephen D

October 14, 2022

Your operators are always courteous and knowledgeable. Very good service.


October 13, 2022

I've been a Canadian Med Center customer for about 6 years now. In all that time there was never once that I considered taking my business elsewhere. They do a great job and the people they contract with are also super.


October 5, 2022

Cheaper and efficient.

Dorothy Serrie S

October 4, 2022

Always appreciate their prompt service but especially appreciate their hanging in there when there was difficulty getting my doctor to renew my prescription!

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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